Does neuroblastoma affect the eyes?

Other signs and symptoms that may indicate neuroblastoma include: Lumps of tissue under the skin. Eyeballs that seem to protrude from the sockets (proptosis) Dark circles, similar to bruises, around the eyes.

What is Omas syndrome?

Opsoclonus-myoclonus-ataxia syndrome (often referred to as OMAS or opsoclonus-myoclonus syndrome) is an autoimmune disorder of the nervous system characterized by new movements of the limbs and eyes, abnormal behaviors, sleep dysregulation, and difficulty talking.

What do signs symptoms do you see with neuroblastoma?

Symptoms include: Bump or lump in the neck, chest, pelvis or abdomen (belly), or several lumps just under the skin that may appear blue or purple (in infants). Bulging eyes or dark circles under eyes (it may look like the child has a black eye). Diarrhea, constipation, upset stomach or loss of appetite.

What causes raccoon eyes in neuroblastoma?

The characteristic ”raccoon eyes” appearance associated with neuroblastoma is probably related to obstruction of the pal- pebral vessels by tumor tissue in and around the orbits [2].

How long can you live with neuroblastoma?

Low-risk group: Children in the low-risk group have a 5-year survival rate that is higher than 95%. Intermediate-risk group: Children in the intermediate-risk group have a 5-year survival rate of around 90% to 95%. High-risk group: Children in the high-risk group have a 5-year survival rate of around 50%.

What does opsoclonus look like?

Opsoclonus-myoclonus syndrome (OMS) is a rare disorder that affects the nervous system. Symptoms include rapid, multi-directional eye movements (opsoclonus), quick, involuntary muscle jerks (myoclonus), uncoordinated movement (ataxia), irritability, and sleep disturbance. The disease may become chronic.

Can neuroblastoma cause nystagmus?

Opsoclonus should be differentiated from nystagmus and ocular flutter. Opsoclonus may be associated with neuroblastoma in children and small-cell lung cancer in adults, as a paraneoplastic manifestation. Frequently, opsoclonus is seen with ataxia of stance and gait as well limbs and truncal myoclonus jerks.

How fast does neuroblastoma progress?

Some neuroblastomas grow slowly (and some might even shrink or go away on their own), while others can grow quickly and spread to other parts of the body. Neuroblastoma happens most often in babies and young children. It is rare in children who are more than 10 years old.

Can opsoclonus be intermittent?

Opsoclonus/ocular flutter. Opsoclonus, also referred to as “saccadomania” or dancing eyes, is a rare, but striking saccade disorder, characterized by intermittent involuntary bursts of wild conjugate multidirectional back to back saccades.

What is the cause of dancing eyes?

Nystagmus is caused by a miscommunication between the eye and the brain and affects the way our brains interpret movement signals from the eye. Nystagmus is typically caused by brain injuries and is a result of brain damage. This eye condition may be referred to as “dancing eyes” because of the repetitive eye movement.

What does dancing eye syndrome look like?

Dancing Eye Syndrome (DES; also known as Ospoclonus Myoclonus Syndrome, OMS) is a rare condition characterised by unusual eye movements, which are almost always present, along with unsteadiness, jerky movements of the trunk and limbs, irritability and sleep disturbance.