What is Arrhenoblastoma?

Listen to pronunciation. (uh-REE-noh-blas-TOH-muh) A rare type of ovarian tumor in which the tumor cells secrete a male sex hormone. This may cause virilization (the appearance of male physical characteristics in females).

What is a Brenner tumor?

Brenner tumor is a rare ovarian tumor that is a part of the surface epithelial group of ovarian neoplasm. It is usually asymptomatic and most of the times it is an incidental pathological finding. Here we present a case of benign Brenner tumor of ovary treated surgically.

What percentage of Leydig cell Tumours is malignant in females?

They are generally benign tumors with only 5% to 10% being considered malignant and have a bimodal distribution with peaks in the prepubertal age group and between the ages of 30 to 60. Due to Leydig cells’ hormonally active properties, they can present with precocious puberty, breast tenderness, or gynecomastia.

Is Brenner tumor benign?

Brenner tumor of the ovary is a solid, abnormal growth (tumor) on the ovary. Most Brenner tumors are not cancerous (benign). These tumors most often occur in women after menopause. They usually do not cause symptoms unless they are very large.

How common is a Brenner tumor?

Brenner tumor is a very rare tumor (adenofibroma) of the ovary representing 5% of all ovarian tumors 1).

Are granulosa cell tumor benign or malignant?

Introduction. Ovarian granulosa cell tumor (GCT) is a malignant tumor originating from the sex-cord stromal cells of the ovary. It is an uncommon primary malignant tumor of the ovary and represents 2% to 5% of all ovarian cancers [1].

Are Leydig cell tumors benign?

Leydig cell tumors are usually benign, but appproximately 10% are malignant. As with germ cell tumors, the route of spread is hematogenous and lymphatic to the retroperitoneal lymph nodes. Unlike germ cell tumors, however, Leydig cell tumors show relative lack of sensitivity to radiotherapy and chemotherapy agents.

Are Leydig cell tumors malignant?

Leydig cell tumors demonstrate malignancy by metastasizing. Approximately 10% of Leydig cell tumors in adults exhibit malignant behavior. The only treatment for malignant Leydig cell tumors is retroperitoneal lymph node dissection, as they are resistant to chemotherapy and radiation.

Are Brenner tumors malignant?

Brenner tumors can be further classified as benign, proliferative (borderline), or malignant by histopathological review. The majority of these tumors are benign or proliferative, with malignant Brenner tumors (MBT) making up <5% of all diagnosed Brenner tumors.

Is Brenner tumor bilateral?

Usually, benign Brenner tumors are unilateral and malignant Brenner tumors are bilateral(21).