What are the guidelines in dosing propofol in patient?

For induction of anaesthesia Propofol should be titrated (approximately 20 – 40 mg propofol every 10 seconds) against the response of the patient until clinical signs show the onset of anaesthesia. Most adult patients aged less than 55 years are likely to require 1.5 to 2.5 mg propofol/kg body weight.

When should propofol not be used?

Use of this medicine to induce anesthesia in children younger than 3 years of age and to maintain anesthesia in children younger than 2 months of age is not recommended. Safety and efficacy have not been established in children for other approved conditions.

How much propofol can you bolus?

MAINTENANCE OF GENERAL ANESTHESIA (INTERMITTENT BOLUS): Most patients require 100 to 150 mcg/kg/min (6 to 9 mg/kg/h) for 3 to 5 minutes or a slow injection of 0.5 mg/kg over 3 to 5 minutes followed immediately by a maintenance infusion.

Why is propofol contraindicated?

Propofol Injectable Emulsion is contraindicated in patients with a known hypersensitivity to propofol or any of Propofol Injectable Emulsion components. Propofol Injectable Emulsion is contraindicated in patients with allergies to eggs, egg products, soybeans or soy products.

Can nurses bolus propofol?

Conclusions: Trained nurses and endoscopists can administer propofol safely for endoscopic procedures. Nurse-administered propofol sedation is one potential solution to the high cost associated with anesthetist-delivered sedation for endoscopy.

What is propofol overdose?

Abstract. Propofol is a potent intravenous anesthetic agent that rapidly induces sedation and unconsciousness. The potential for propofol dependency, recreational use and abuse has only recently been recognized and several cases of accidental overdose and suicide have emerged.

Can you overdose on propofol?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur. Propofol can cause severe drowsiness or dizziness, which may last for several hours. You will need someone to drive you home after your surgery or procedure.