What is the pharmacology of penicillin?

Penicillin kills bacteria by inhibiting the completion of the synthesis of peptidoglycans, the structural component of bacterial cell wall. It specifically inhibits the activity of enzymes that are needed for the cross-linking of peptidoglycans during the final step in cell wall biosynthesis.

What is the pharmacodynamics of penicillin?

When large amounts of penicillin are available, the enzyme is completely blocked. When small amounts of penicillin are available, the enzyme resumes normal function. Thus the bacterial-killing activity of penicillin changes as drug levels in the body change. This is considered the “pharmacodynamics” of penicillin.

What are the names of penicillin drugs?

Description and Brand Names

• Amoxil.
• Bactocill.
• Bicillin L-A.
• Cloxapen.
• Crysticillin.
• Dynapen.
• Geocillin.
• Nafcil.

What is the function of penicillin?

Penicillin prevents the bacteria from synthesizing peptidoglycan, a molecule in the cell wall that provides the wall with the strength it needs to survive in the human body. The drug greatly weakens the cell wall and causes bacteria to die, allowing a person to recover from a bacterial infection.

What are the properties of penicillin?

Penicillins are bactericidal beta-lactam antibiotics that inhibit bacterial cell wall synthesis. A natural product, the penicillin structure has been modified to prepare a variety of semi-synthetic agents. The spectrum of antibacterial activity varies with each class of the penicillin family.

What are the general properties of penicillins?

What are the indications of penicillin?

penicillin G procaine (Rx)

• Pneumonia. Indicated for moderately severe uncomplicated pneumococcal pneumonia.
• Streptococcal Infections (Group A)
• Staphylococcal Infections.
• Bacterial Endocarditis.
• Syphilis.
• Anthrax.
• Diphtheria.
• Vincent’s Infection (fusospirochetosis)

What are the benefits of penicillin?

Today, penicillin, considered the first wonder drug, is used to treat throat infections, meningitis, syphilis and other bacterial infections. It works by inhibiting enzymes involved in building bacterial cell walls and by activating other enzymes that break these protective barriers down.

What are the uses of penicillin?

Penicillins are used in the treatment of throat infections, meningitis, syphilis, and various other infections. The chief side effects of penicillin are hypersensitivity reactions, including skin rash, hives, swelling, and anaphylaxis, or allergic shock.

What is difference between penicillin and amoxicillin?

The main difference between amoxicillin and penicillin is that amoxicillin is effective against a wider spectrum of bacteria compared with penicillin. Both amoxicillin and penicillin belong to the class of antibiotics called penicillins.

What is penicillin best used for?

What is the most common use for penicillin? Penicillin is used to treat a variety of bacterial infections, including meningitis, pneumonia, gonorrhea, syphilis, and endocarditis.