Can DCIS be multifocal?

Multifocality was a pathologic feature defined as more than one distinct focus of DCIS, with at least 5 mm of intervening healthy tissue confined to a single quadrant of the breast. For cases with multifocal DCIS, the size of the largest focus was recorded.

Are there different stages of DCIS?

There are 5 major stages of breast cancer: stage 0 (zero), which is non-invasive ductal carcinoma in situ (DCIS), and stages I through IV (1 through 4), which are used for invasive breast cancer. The stage provides a common way of describing the cancer, so doctors can work together to plan the best treatments.

What stage cancer is DCIS?

DCIS is also called intraductal carcinoma or stage 0 breast cancer. DCIS is a non-invasive or pre-invasive breast cancer. This means the cells that line the ducts have changed to cancer cells but they have not spread through the walls of the ducts into the nearby breast tissue.

What does multifocal disease mean?

Breast cancers are defined as multifocal when there is more than one distinct tumour within the same quadrant of the breast (MF) and multicentric when multiple cancers develop in different quadrants of the breast (MC) [5].

What stage is high grade DCIS?

DCIS that is high grade, is nuclear grade 3, or has a high mitotic rate is more likely to come back (recur) after it is removed with surgery. DCIS that is low grade, is nuclear grade 1, or has a low mitotic rate is less likely to come back after surgery.

How fast does DCIS progress?

It assumes that all breast carcinomas begin as DCIS and take 9 years to go from a single cell to an invasive lesion for the slowest growing lesions, 6 years for intermediate growing DCIS lesions, and 3 years for fast-growing DCIS lesions.

What does multifocal mean in cancer?

How serious is DCIS cancer?

DCIS is non-invasive because it hasn’t spread beyond the milk ducts into other healthy tissue. DCIS isn’t life-threatening, but if you’re diagnosed with DCIS, you have a higher-than-average risk of developing invasive breast cancer later in life.

What percentage of DCIS is Grade 3?

There was no significant difference in the distribution of grades between the DCIS detected by mass screening and the DCIS not detected by mass screening (from the interval group); 16.4–18.8 % were low grade, 27.2–31.6 % were intermediate grade, and 52.0–54.0 % were high grade (Table 3).

What is the treatment for multifocal breast cancer?

There are several treatment options available for multifocal breast cancer. These include lumpectomy, mastectomy, radiation therapy, hormonal therapy, and chemotherapy.