Do fibrates prevent stroke?

Do fibrates prevent stroke?

Our analysis showed that when compared primarily to placebo, fibrates can be effective for prevention of composite outcome of non‐fatal stroke, non‐fatal heart attack (myocardial infarction), and death due to circulatory disease.

What are the side effects of fibrates?

The side effects of fibrates include nausea, stomach upset, and sometimes diarrhea. Fibrates can irritate (inflame) the liver. The liver irritation usually is mild and reversible, but it occasionally can be severe enough to require stopping the drug. Fibrates can cause gallstones when used for several years.

What medication can replace fenofibrate?

Fenofibrate Alternatives Compared

  • Vascepa.
  • TriCor.
  • Omega-3 polyunsaturated fatty acids.
  • Trilipix.
  • Lipofen.
  • Rosuvastatin.

Is fenofibrate safer than a statin?

At the end of the study, the group that took gemfibrozil had a 34 percent decrease in the risk of coronary heart disease, but there was no difference in the death rate. Overall, statins appear to have greater benefit than fibrates in decreasing the risk of both heart attacks and strokes.

How long should I take fenofibrate?

Monitoring of cholesterol/triglyceride levels every four to eight weeks is important to establish the effectiveness of fenofibrate therapy. Your doctor should consider discontinuing therapy if you have not had an adequate response after two months of treatment.

How long can I take fenofibrate?

What foods have fibrates?

Other excellent sources include beans, barley, prunes, citrus fruits, apples, Brussels sprouts, broccoli, and apricots. Psyllium, a natural grain from India, is also rich in soluble fiber. It is not part of the American diet, but you can get it in supplements such as Metamucil or Perdiem Fiber.

When do you stop fibrates?

Discontinue fibrate therapy or reduce the fibrate dose if a clinically significant elevation of serum creatinine occurs in the patient, after excluding all possible causes for the same.

Can you stop taking fenofibrate suddenly?

Fenofibrate oral tablet is used for long-term treatment. It comes with risks if you don’t take it as prescribed. If you stop taking the drug suddenly or don’t take it at all: Your cholesterol levels may not be controlled. This raises your risk of serious health problems such as heart disease, heart attack, or stroke.

Can fenofibrate be taken long term?

How long can you stay on fenofibrate?