How will synthesis p-nitroaniline from acetanilide?

The organic compound p-nitroacetanilide is prepared from acetanilide through nitration. When acetanilide is treated with nitrating mixture that is a mixture of nitric acid and sulphuric acid p-nitroacetanilide is formed. Along with p-nitroacetanilide, o-nitroacetanilide is also formed as a minor product.

How will you convert acetanilide to p-nitroaniline in two steps?

Add dry acetanilide (25 g) to glacial acetic acid (25 ml) in a beaker and then introduce concentrated sulphuric acid (50 ml) slowly with constant stirring to obtain clear solution. Place the beaker in a freezing mixture of ice and salt to cool the solution below 5 oC.

How do you get p-nitroaniline from aniline?

1. Step 1: Acetylation of Aniline. In the first step we need to put the removable acetyl protecting group on the.
2. Step 2: Nitration of Acetanilide. In this step you first form the nitronium ion in situ by dehydration of nitric acid.
3. Step 3: Preparation of p-Nitroaniline.

What is p-nitroaniline used for?

p-Nitroaniline is a bright yellow powder with a faint Ammonia-like odor. It is used as an intermediate in the manufacture of dyes, pharmaceuticals and pesticides.

Why is p-nitroaniline colored?

Trouble is that traces of acid left will hydrolyze it into p-nitroaniline which has deep yellow to yellow-orange color (this compound has melting point of 146 -149 °C) and it smells like ammonia. Unfortunately, p-nitroaniline is difficult to remove from p-nitroacetanilide by crystallization.

How can you convert aniline to p-nitroaniline give chemical equations only?

Aniline when treated with acetoacetate will produce Nacetyl aniline. This if treated with H2SO4/HNO2/CH3COOH will produce paranito nacetyl aniline, which on hydrolysis will give para nito aniline.

What is the structure of p-nitroaniline?

C6H6N2O24-Nitroaniline / Formula

Is p-nitroaniline an acid or a base?

Secondly, aniline and p-nitroaniline (first two green shaded structures) are weaker bases due to delocalization of the nitrogen non-bonding electron pair into the aromatic ring (and the nitro substituent). This is the same delocalization that results in activation of a benzene ring toward electrophilic substitution.

How is P bromoaniline prepared from aniline?

A preparation method for para-bromoaniline take aniline as raw material, first under zinc powder effect, generates Acetanilide with acetic acid generation acetylization reaction, then generates asepsin with bromine reaction, obtains para-bromoaniline finally by hydrolysis, neutralization reaction.

How is acetanilide converted to p-bromoaniline?

Aniline is heated with acetic anhydride to form acetanilide. Treatment with bromine/acetic acid gives p-bromoacetanilide. Acid/alkaline hydrolysis gives p-bromoaniline.

What is the mechanism of acetanilide?

Acetanilide is prepared from aniline when it reacts with acetic anhydride/glacial acetic acid in the presence of zinc dust. A mixture of aniline, glacial acetic acid, acetic anhydride and zinc dust is refluxed under anhydrous condition and then poured the mixture into ice cold water to get acetic anhydride precipitate.