Is Phenergan injection safe in pregnancy?
Is Phenergan injection safe in pregnancy?
Phenergan Injection should not be used in pregnancy unless the physician considers it essential. The use of Phenergan is not recommended in the 2 weeks prior to delivery in view of the risk of irritability and excitement in the neonate. Available evidence suggests that the amount excreted in milk is insignificant.
How much Phenergan can I take while pregnant?
Phenergan is not recommended for use during pregnancy. If there is a need to consider Phenergan during your pregnancy, your pharmacist or doctor will discuss with you the benefits and risks of taking it. Do not take Phenergan if you are breastfeeding or plan to breastfeed.
Is Phenergan DM safe in pregnancy?
Dextromethorphan / promethazine Pregnancy Warnings US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Why is Phenergan used in pregnancy?
What is it? Promethazine (Phenergan®) is a sedating (drowsy) antihistamine that is used to treat allergies, nausea and vomiting (including in pregnancy), and for short-term treatment of some sleep problems.
Is Phenergan safe in third trimester?
Both Promethazine (Phenergan) and Ondansetron (Zofran) have been shown to be very effective with no adverse effects on the fetus. Ondansetron is less sedating. Reglan (Metoclopramide) and Compazine (Prochlorperazine) are also effective agents with no known adverse effects on the fetus.
What class is Phenergan for pregnancy?
Pharmacologic Therapy for Nausea and Vomiting of Pregnancy
| Medication | Pregnancy category |
|---|---|
| Prochlorperazine (Compazine) | C |
| Promethazine (Phenergan) | C |
| Trimethobenzamide (Tigan) | C |
| Ondansetron (Zofran) | B |
Does promethazine cross the placenta?
Phenothiazine agents (e.g., promethazine and prochlorperazine) cross the placenta and are eliminated from fetal and neonatal tissue more slowly than in adults, but have not been shown to be teratogenic.
What pregnancy category is Phenergan?
Pharmacologic Therapy for Nausea and Vomiting of Pregnancy
| Medication | Pregnancy category |
|---|---|
| Promethazine (Phenergan) | C |
| Trimethobenzamide (Tigan) | C |
| Ondansetron (Zofran) | B |
| Droperidol (Inapsine) | C |
Can Phenergan cause birth defects?
Over 5,000 women taking promethazine in early pregnancy have been studied as it is used quite commonly to treat pregnancy sickness. These studies do not raise concern of a link with birth defects in the baby.
Why is Phenergan given in pregnancy?
Does Phenergan help with pregnancy nausea?