What can trigger pemphigus vulgaris?

What causes pemphigus vulgaris? Pemphigus vulgaris is not fully understood. Experts believe that it’s triggered when a person who has a genetic tendency to get this condition comes into contact with an environmental trigger, such as a chemical or a drug.

How do you get rid of pemphigus?

Treatment usually begins with medications that are intended to suppress blister formation. It’s generally more effective when it begins as early as possible. If use of a drug triggered your condition, stopping use of it may be enough to clear up your pemphigus.

What drugs can cause pemphigus?

Drugs that cause pemphigus include:

• Thiol drugs, including penicillamine, captopril.
• Antibiotics: penicillins, cephalosporins, vancomycin.
• Antihypertensive drugs: other angiotensin-converting enzyme inhibitors such as cilazapril, lisinopril, enalapril.
• Piroxicam.

Is pemphigus vulgaris a disability?

Pemphigus and pemphigoid are a group of rare autoimmune diseases that affect the skin and mucous membranes causing painful blistering and scarring. For some patients, the noticeable and sometimes life-threatening, symptoms are too much to work with.

What is pemphigus vulgaris?

Pemphigus is a rare group of autoimmune diseases. It causes blisters on the skin and mucous membranes throughout the body. It can affect the mouth, nose, throat, eyes, and genitals. Pemphigus vulgaris is the most common type of pemphigus.

What are desmosomes in pemphigus vulgaris?

Pemphigus vulgaris is an autoimmune blistering disease. The keratinocytes are cemented together at unique sticky spots called desmosomes. In pemphigus vulgaris, immunoglobulin type G ( IgG) autoantibodies bind to a protein called desmoglein 3 (dsg3), which is found in desmosomes in the keratinocytes near the bottom of the epidermis.

What are the long term effects of pemphigus vulgaris?

Pemphigus vulgaris and its treatments can be debilitating and may cause lost time at work, weight loss, loss of sleep, and emotional distress. Connecting with others facing the same concerns and challenges can help a person cope with the changes the disease causes in their life.

What is the best treatment for pemphigus vulgaris?

Treatment of pemphigus vulgaris. The primary aim of treatment is to decrease blister formation, prevent infections and promote healing of blisters and erosions. Oral corticosteroids are the mainstay of medical treatment for controlling the disease.