What conditions can be diagnosed with hemoglobin electrophoresis?

Hemoglobin electrophoresis measures hemoglobin levels and looks for abnormal types of hemoglobin. It’s most often used to help diagnose anemia, sickle cell disease, and other hemoglobin disorders.

What causes Hb electrophoresis?

If your results show abnormal hemoglobin levels, they may be caused by: hemoglobin C disease, a genetic disorder that leads to severe anemia. rare hemoglobinopathy, a group of genetic disorders causing the abnormal production or structure of red blood cells. sickle cell anemia.

What does electrophoresis test for?

What is this test? Protein electrophoresis is a test that measures specific proteins in the blood. The test separates proteins in the blood based on their electrical charge. The protein electrophoresis test is often used to find abnormal substances called M proteins.

What does it mean to have abnormal hemoglobin?

A hemoglobin test measures the levels of hemoglobin in your blood. Hemoglobin is a protein in your red blood cells that carries oxygen from your lungs to the rest of your body. If your hemoglobin levels are abnormal, it may be a sign that you have a blood disorder. Other names: Hb, Hgb.

Can all abnormal hemoglobin be diagnosed by electrophoresis?

Patients should be screened with a hemoglobin electrophoresis which is able to detect not only the abnormal hemoglobin S of sickle cell anemia, but also other abnormal hemoglobin variants which may cause disease. Solubility testing such as the Sickledex is not sufficient.

What is normal range of Hb electrophoresis?

Normal Results HbA: 95% to 98% (0.95 to 0.98) HbA2: 2% to 3% (0.02 to 0.03) HbE: Absent. HbF: 0.8% to 2% (0.008 to 0.02)

What is thalassemia and its symptoms?

Overview. Thalassemia (thal-uh-SEE-me-uh) is an inherited blood disorder that causes your body to have less hemoglobin than normal. Hemoglobin enables red blood cells to carry oxygen. Thalassemia can cause anemia, leaving you fatigued. If you have mild thalassemia, you might not need treatment.