What disease does Mycobacterium tuberculosis cause?

What disease does Mycobacterium tuberculosis cause?

Tuberculosis (TB) is a contagious disease caused by infection with Mycobacterium tuberculosis (Mtb) bacteria. It is spread through the air when a person with TB disease of the lungs or throat coughs, speaks or sings, and people nearby breathe in these bacteria and become infected.

What are two diseases caused by Mycobacterium?

Mycobacterium abscessus [mī–kō–bak–tair–ee–yum ab–ses–sus] (also called M. abscessus) is a bacterium distantly related to the ones that cause tuberculosis and Hansen’s Disease (Leprosy).

Which bacteria causes typhoid and cholera?

TF is mainly caused by Salmonella typhi, whereas cholera is caused by intestinal infection by the toxin-producing bacterium Vibrio cholerae.

What are the different types of Mycobacterium tuberculosis?

These species are, with the exception of M. bovis BCG, considered to cause tuberculosis (TB) in humans and animals….This complex comprises the following species:

  • M. tuberculosis.
  • M. bovis (subsp. bovis and caprae)
  • vaccine strain M. bovis BCG (Bacille Calmette-Guérin)
  • M. africanum.
  • M. canettii.
  • M. microti.
  • M. pinnipedii.

What is mycobacterial disease?

Nontuberculous mycobacterial disease (NTM) is a general term for a group of lung infections caused by exposure to mycobacteria found in soil and water. The mycobacteria causing these diseases exclude those that cause tuberculosis and leprosy.

What is the cause of extrapulmonary TB?

Summary. Extrapulmonary tuberculosis (EPTB) is an infectious disease caused by Mycobacterium tuberculosis that occurs in organ systems other than the lungs. Epidemiologic risk factors include birth in high TB-prevalent countries, exposure at place of residence/work in an institutional setting, and homelessness.

What are extrapulmonary symptoms?

Symptoms include fever, chills, weakness, malaise, and often progressive dyspnea. Intermittent dissemination of tubercle bacilli may lead to a prolonged fever of unknown origin (FUO).

What disease is dysentery?

Dysentery is an infection of the intestines that causes diarrhoea containing blood or mucus. Other symptoms of dysentery can include: painful stomach cramps. feeling sick or being sick (vomiting)

What is the virulence of rv0288 in tuberculosis (TB) infection?

TB10.4, the product of Rv0288, is recognized by sera from 70% of TB patients, and T cells from this cohort show a strong cytokine response (IFN-γ release) when the protein is presented (265). The role of the virulence of Rv0288 in virulence has not been analyzed yet, but experiments are in progress.

Is Mycobacterium tuberculosis (TB) more virulent than other clinical isolates?

Mycobacterium tuberculosisCDC1551 induces a more vigorous host response in vivo and in vitro, but is not more virulent than other clinical isolates. J. Immunol.162:6740-6746.

How is the virulence of Mycobacterium tuberculosis (TB) determined in mice?

Virulence of a Mycobacterium tuberculosisclinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-alpha/beta. Proc. Natl. Acad. Sci. USA98:5752-5757. [PMC free article][PubMed] [Google Scholar] 179. Manganelli, R., E. Dubnau, S. Tyagi, F. M. Kramer, and I. Smith.1999.

What causes loss of virulence in Mycobacterium tuberculosis?

Collins, D. M., R. P. Kawakami, G. W. de Lisle, L. Pascopella, B. R. Bloom, and W. R. Jacobs, Jr.1995. Mutation of the principal sigma factor causes loss of virulence in a strain of the Mycobacterium tuberculosiscomplex.