What does a low Anticardiolipin IgM mean?
What does a low Anticardiolipin IgM mean?
What does it mean if your CARDIOLIPIN AB (IGM) result is too low? A negative anticardiolipin IgG or IgM result indicates that this type of antibody was not present or was present in too small a quantity in the blood sample being tested.
What does Anticardiolipin IgG mean?
IgG is the anticardiolipin antibody type most associated with complications. An enzyme-linked immunosorbent assay (ELISA) is used to test for anticardiolipin antibodies. One can test for all isotypes at once, or they can be detected separately.
What does Anticardiolipin IgM test for?
Description. The Anticardiolipin Antibodies Test, or ACA Blood Test, aids in the diagnosis of antiphospholipid syndrome (APS). APS is an autoimmune disorder that produces anticardiolipin antibodies. These antibodies interfere with the blood clotting process, which can result in inappropriate or excessive clotting.
Can you have lupus with a negative lupus anticoagulant?
When a person is initially negative for lupus anticoagulant but has an autoimmune disease such as lupus, a healthcare practitioner may occasionally repeat one or more of the lupus anticoagulant screening tests, usually the PTT, to determine whether the antibody has developed since the last time the test was performed.
What does a negative Anticardiolipin test mean?
There are three types of anticardiolipin antibodies: IgG, IgA and IgM. The test measures IgG and IgM levels. A negative anticardiolipin IgG or IgM result indicates that this type of antibody was not present or was present in too small a quantity in the blood sample being tested.
What does a negative cardiolipin test mean?
A negative result means only that cardiolipin antibodies are not present or not present at a detectable level in the blood at the time of the test. Cardiolipin antibodies are the most common of the antiphospholipid antibodies.
What is the normal range for antiphospholipid syndrome?
The reference range findings are as follows: Less than 15 immunoglobulin G (IgG) phospholipids units (GPL): Absent or none detected. Less than 12 immunoglobulin M (IgM) phospholipids units (MPL): Absent or none detected.
What is cardiolipin IgA antibody?
Cardiolipin antibodies are the most common antiphospholipid antibody, a group of autoantibodies associated with excessive clotting and autoimmune diseases, such as lupus. They are frequently detected with other antiphospholipid antibodies, such as lupus anticoagulant and anti-beta-2 glycoprotein 1.
What tests confirm antiphospholipid syndrome?
To diagnose APS, the blood needs to be tested for the abnormal antiphospholipid antibodies that increase the risk of blood clots. This requires a blood test specifically designed to look for these antibodies.
Is antiphospholipid antibody syndrome the same as lupus?
Antiphospholipid syndrome (APS) is the association of thrombosis and/or pregnancy morbidity with antiphospholipid antibodies (aPL). Thirty to forty percent of systemic lupus erythematosus (SLE) patients are tested positive for aPL, which may have an impact on the SLE presentation, management, and prognosis.
What test confirms lupus?
Antinuclear antibody (ANA) test. A positive test for the presence of these antibodies — produced by your immune system — indicates a stimulated immune system. While most people with lupus have a positive ANA test, most people with a positive ANA do not have lupus.
What does a negative anticardiolipin test mean?
When should you suspect antiphospholipid syndrome?
A diagnosis of APS can usually be confirmed if you have had: 1 or more confirmed blood clots. 1 or more unexplained late miscarriages at or after week 10 of your pregnancy. 1 or more premature births at or before week 34 of your pregnancy.