What drug class is Thalitone?

Thalitone is a prescription medicine used to treat the symptoms of High Blood Pressure (Hypertension), Swelling (Edema) and Heart Failure. Thalitone may be used alone or with other medications. Thalitone belongs to a class of drugs called Diuretics, Thiazide.

What is Thalitone prescribed for?

Chlorthalidone is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to reduce extra salt and water in the body caused by conditions such as heart failure, liver disease, and kidney disease.

Who makes Thalitone?

It’s also been useful in treating edema in people with congestive heart failure, cirrhosis of the liver or kidney disorders. Pharmaceutical giant Pfizer previously manufactured 15 mg chlorthalidone tablets under the brand name Thalitone, but Thalitone was later pulled from the market.

What do you monitor chlorthalidone with?

Fluid status and Blood pressure: All patients taking chlorthalidone to require observation for dryness of mouth, thirst, lethargy, hypotension, oliguria, tachycardia, palpitations, and gastrointestinal disturbances, such as nausea and vomiting.

What is the generic name for chlorthalidone?

Chlorthalidone is available under the following different brand names: Hygroton, Thalitone, and Chlorthalid.

Is chlorthalidone the same as HCTZ?

There are significant pharmacokinetic and pharmacodynamic differences between these diuretics. Chlorthalidone is ≈1.5 to 2.0 times as potent as hydrochlorothiazide, and the former has a much longer duration of action. Whether these pharmacokinetic and pharmacodynamic features cause differences in outcomes is not known.

Is Thalitone the same as chlorthalidone?

Thalitone (chlorthalidone) is a thiazide diuretic used in the treatment of high blood pressure, congestive heart failure, and edema (fluid retention). The brand name Thalitone is discontinued in the U.S. constipation.

Is chlorthalidone discontinued?

THALITONE (chlorthalidone USP) tablets, 15 mg, are currently listed in the “Discontinued Drug Product List” section of the Orange Book.

Is chlorthalidone made by Pfizer?

What drugs should not be taken with chlorthalidone?

Chlorthalidone may interact with other medications

• Blood pressure drugs. When chlorthalidone is taken with other medications that lower your blood pressure, your blood pressure may become dangerously low.
• Diabetes drugs. Your doctor may need to adjust the dose of your diabetes medication.
• Digoxin.
• Lithium.

Which is safer chlorthalidone or hydrochlorothiazide?

HCTZ and chlorthalidone are both safe and cheap first-line blood pressure medications, but the evidence is clear—chlorthalidone is better.

Is there a substitute for chlorthalidone?

The main diuretic used today is hydrochlorothiazide, or HCTZ, which has fewer side effects than chlorthalidone, the diuretic used in this study.

Why is HCTZ prescribed over chlorthalidone?

Evidence-Based Answer. Chlorthalidone produces slightly greater reductions in blood pressure compared with hydrochlorothiazide (HCTZ), but it is associated with greater declines in serum potassium levels.

What is the difference between chlorothiazide and hydrochlorothiazide?

HCTZ has one additional hydrogen substituted on a nitrogen on the sulfonamide ring compared with chlorothiazide. All thiazides have a similar dual-ring structure.

Which is better HCTZ or chlorthalidone?

Chlorthalidone is better at lowering the risk of a cardiovascular event, such as a heart attack. Even after chlorthalidone and HCTZ achieve the same blood pressure, chlorthalidone lowers the risk of a cardiovascular event by about 20% more than HCTZ.

Which is better chlorthalidone or amlodipine?

Chlorthalidone was associated with a small but significantly lower systolic pressure over the course of the study than amlodipine or lisinopril (133.9 versus 134.7 and 135.9 mmHg, respectively) and a higher proportion of patients who attained the blood pressure goal of less than 140/90 mmHg (68.2 versus 66.3 and 61.2 …

What 3 blood pressure meds did Pfizer recall?

The affected products in that recall are quinapril HCl/hydrochlorothiazide (Accuretic) tablets that Pfizer distributes, and two authorized generics, quinapril plus hydrochlorothiazide and quinapril HCl/hydrochlorothiazide, distributed by Greenstone.

Can you take vitamin D with chlorthalidone?

Using chlorthalidone together with cholecalciferol can cause your blood calcium levels to become too high. Contact your doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures.