What is an icteric sample?

Unconjugated Bilirubin. Icterus, also known as jaundice, is used to describe the yellowish-greenish color observed in the sclera of the eyes or in plasma/serum samples of patients with very high concentrations of bilirubin.

What does icteric index mean?

Icterus (or the icterus index) is a measure of the yellow colour of serum. This colour is normally due almost exclusively to the presence of bilirubin, a hemoglobin waste product from the red blood cells.

What causes a sample to be icteric?

Icteric serum is caused by the presence of excess bilirubin in the blood stream. Icteric serum is caused by the presence of excess bilirubin in the blood stream as a result of increased production (pre-hepatic) or inappropriate excretion (hepatic and post-hepatic).

What tests does icterus affect?

In conclusion, this study shows that only some biochemical laboratory tests are impacted by icterus. For FRUC, HDLc, PROT, Phos, UA, TG, and CREA, we propose a method of estimating the interference‐free value.

What is Icteric interference?

At a broad level, the two main mechanisms for icteric interference are spectral interference or chemical reactivity with assay reagents [13,14]. The spectral properties of bilirubin can cause interference with oximetry, co-oximetry, and methemoglobin measurements [3].

What is icteric interference?

What is an expected effect on the results for an Icteric sample?

What would be an expected effect on the results for this sample? An icteric sample would have a spectral interference effect on the results. Volume displacement could occur with either lipemia or hyperproteinemia. Release of enzymes or analytes would occur in a hemolyzed sample.

Does icterus affect CBC?

Icterus has minimal to no effect on hematologic results, including plasma protein measured by refractometry (Gupta & Stockham 2014).