What is cutaneous lymphoid hyperplasia?

Cutaneous lymphoid hyperplasia (CLH) is considered a benign lymphoid reactive process that results from various antigenic stimuli and may have potential for progression to overt lymphoma. CLH lesions may closely resemble lymphoma both clinically and histologically.

Is Pseudolymphoma curable?

Cases of cutaneous pseudolymphoma documented to occur as a result of infection should be appropriately treated. In idiopathic cases of cutaneous pseudolymphoma, treatment is not mandatory. Cures may be effected via surgical removal, cryosurgery, or local irradiation.

What causes Pseudolymphoma?

Pseudolymphoma, also called as cutaneous lymphoid hyperplasia, is a skin lesion having lymphomatous appearance mimicking lymphoma that results from known or unknown stimulus like insect bites, vaccination, trauma, folliculitis, drugs, jewelry, and contactants.

What does Pseudolymphoma look like?

Pseudolymphomatous drug eruption due to captopril, marked by erythematous to purple papules, patches, and plaques. This erythrodermic pseudolymphoma (T-cell pattern) typifies drug-induced pseudolymphoma, which is most often secondary to anticonvulsant therapy.

How is cutaneous lymphoid hyperplasia treated?

The treatment is penicillin. Rare cases progress to true lymphoma. Histologic examination of nodular cutaneous lymphoid hyperplasia reveals a dense, nodular infiltrate that occupies primarily the dermis and lessens in the deeper dermis and subcutaneous fat (i.e., it is “top-heavy”).

Can Pseudolymphoma turn into lymphoma?

Although rare, reports of cutaneous B-cell pseudolymphoma evolving into B-cell lymphoma have been described. In one study of 4 cases, transformation of 1 case of pseudolymphoma into a large B-cell lymphoma was identified, similar to our patient [7].

What drugs cause Pseudolymphoma?

Anticonvulsants, typically phenytoin and carbamazepine, are the most frequent cause of drug-induced pseudolymphoma.

Which drugs cause Pseudolymphoma?

What causes cutaneous lymphoid hyperplasia?

It is usually idiopathic but can be caused by tattoos,Borrelia infections, herpes zoster scars, antigen injections, acupuncture, drug reactions, and persistent insect bite reactions. Borrelia-induced cutaneous lymphoid hyperplasia occurs more commonly in young women.

How do you treat a Pseudolymphomatous allergic reaction?

Treatment modalities include topical and intralesional application of glucocorticosteroids as well as surgical excision and laser therapy [7, 9-13]. Additionally, systemic therapy with hydroxychloroquine was effective in a case of tattoo-associated pseudolymphomatous reaction in the green part of the tattoo [8].

Who is at risk for mycosis fungoides?

Who might get mycosis fungoides? Mycosis fungoides can affect anyone but is most common in adults over 50. Men are twice as likely as women to develop mycosis fungoides.