What is DBA2?

GeneCards Summary for DBA2 Gene DBA2 (Diamond-Blackfan Anemia 2) is a Genetic Locus. Diseases associated with DBA2 include Diamond-Blackfan Anemia 2 and Diamond-Blackfan Anemia.

What are DBA 1 mice?

DBA/1J mice are widely used as a model for rheumatoid arthritis: immunization with type II collagen leads to the development of severe polyarthritis mediated by an autoimmune response. DBA/1J mice show an intermediate susceptibility to developing atherosclerotic aortic lesions on an atherogenic diet.

What is C3H?

C3H/HeJ mice, commonly called C3H, are used as a general purpose strain in a wide variety of research areas including cancer, infectious disease, sensorineural, and cardiovascular biology research.

What are CBA mice?

CBA inbred mice are derived from a cross of an unpedigreed Bagg albino female and an early DBA progenitor male. C3H mice are descended from the same cross. The CBA inbred strain was initially bred for longevity and a low incidence of spontaneous mammary tumors (compared with C3H).

What is DBA 2J mice?

DBA/2J is a widely used inbred strain that is valuable in a large number of research areas, including cardiovascular biology, neurobiology, and sensorineural research. Its characteristics are often contrasted with those of the C57BL/6J inbred strain (Stock No. 000664).

What are three characteristics of the DBA 2J from the Jackson Laboratories?

Physical Characteristics The DBA/2J mice have a large, plump body with light brown/greyish brown fur. The original DBA strain was bred specifically to select for this color. They have a low brain weight and a high concentration of red blood cells.

How collagen induces arthritis?

Collagen-induced arthritis (CIA) is an established experimental model of human RA induced by immunization of mice with bovine or chicken type II collagen (CII) emulsified in complete Freund’s adjuvant (CFA) that results in rheumatic symptoms such as joint inflammation and swelling 16.

Where do lab mice come from?

Because of their beginnings in the mouse fancy trade, laboratory mouse strains are a genetic mix of four different subspecies: Mus musculus musculus (eastern Europe), Mus musculus domesticus (western Europe), Mus musculus castaneus (Southeast Asia) and Mus musculus molossinus (Japan).

What is the structural formula for c3h for?

Chemical Component Summary
Identifiers	2-[[(2~{R})-2-azanyl-3-[(3~{S})-3-methyl-1-oxidanyl-hexan-3-yl]sulfanyl-propanoyl]amino]ethanoic acid
Formula	C12 H24 N2 O4 S
Molecular Weight	292.39
Type	NON-POLYMER

Is the authoritative source of official names for mouse genes alleles and strains?

The Mouse Genome Informatics Database is the authoritative source of official names for mouse genes, alleles, and strains. Nomenclature follows the rules and guidelines established by the International Committee on Standardized Genetic Nomenclature for Mice.

What are DBA 2J mice used for?

As one of the most popular mouse model strains, DBA/2J has been used in many areas of medical research, including cardiovascular (especially atherosclerosis), developmental (lymphatic deficits), neurobiological (epilepsy, hearing loss, and glaucoma), and immunological (complement deficiency) research.

Does collagen cause rheumatoid arthritis?

Abstract. Rheumatoid arthritis is an inflammatory synovial disease thought to involve T cells reacting to an antigen within the joint. Type II collagen is the major protein in articular cartilage and is a potential autoantigen in this disease.

Are lab mice cloned?

Lab mice differ in important ways from the common house mouse (mus musculus) that humans have lived with for centuries. For one thing, lab mice are essentially genetic clones of each other—the product of generations of careful inbreeding.

What is the name of c3 H8?

Propane
Propane (c3h8) – an overview | ScienceDirect Topics.