What is pegylated graphene oxide?

PEG functioned GO is a safe drug delivery carrier. As graphene oxide (GO) has functional groups for better bonding, is excellently dispensability within water, and is easy to manufacture3, it is considered highly interesting in biomedical fields including drug delivery4.

What is Nanographene oxide?

Nano-graphene oxide (nano-GO) is a new class of carbon based materials being proposed for biomedical applications due to its small size, intrinsic optical properties, large specific surface area and easy to functionalize.

What drugs have graphene oxide?

Some researchers indicated that graphene oxide can be used as a nanocarrier for loading and delivery19,20,21 of commonly used anticancer drugs such as SN-3822, doxorubicin, camptothecin, and methotrexate23,24.

What does graphene oxide do when injected?

Intraperitoneal Injection of Graphene Oxide Nanoparticle Accelerates Stem Cell Therapy Effects on Acute Kidney Injury. Purpose: Graphene-based nanostructures have shown some degree of stem cell protection against cell death. Acute kidney injury (AKI) is a major cause of mortality in hospitalized patients.

What is graphene oxide nanoparticles?

Graphene oxide (GO), an oxidized derivative of graphene, is currently used in biotechnology and medicine for cancer treatment, drug delivery, and cellular imaging. Also, GO is characterized by various physicochemical properties, including nanoscale size, high surface area, and electrical charge.

How do you functionalize graphene oxide?

Covalent functionalization of graphene oxide through modification of epoxy groups on the basal planes usually involves a nucleophilic attack at the α-carbon of the epoxide, and using an amine group to catalyze the ring-opening reaction.

What is the scientific name for graphene oxide?

Description. Graphene oxide (GO), also referred to as graphite/graphitic oxide, is obtained by treating graphite with oxidisers, and results in a compound of carbon, oxygen, and hydrogen in variable ratios. The structure and properties of GO are much dependent on the particular synthesis method and degree of oxidation.

Why is graphene oxide used in medication?

Graphene and graphene oxide have been widely investigated for biomedical applications due to their exceptional qualities: twodimensional planar structure, wide surface area, chemical and mechanical constancy, sublime conductivity and excellent biocompatibility.

Are there other names for graphene oxide?

Description. Graphene oxide (GO), also referred to as graphite/graphitic oxide, is obtained by treating graphite with oxidisers, and results in a compound of carbon, oxygen, and hydrogen in variable ratios.

Can graphene oxide be used in the human body?

Graphene and graphene oxide (GO), due to their physicochemical properties and biocompatibility, can be used as an innovative biomedical material in biodetection, drug distribution in the body, treating neoplasms, regenerative medicine, and in implant surgery.

Why is graphene oxide used in medicine?

Graphene Oxide Nanoparticles (GO-NPs) have been shown to increase leukocyte numbers such as macrophages and T cells. This effect boosts adaptive immunity, thus allowing for a better immune response and viral clearance, or a possible use as vaccine adjuvants.

How do you functionalize graphene?

The functionalization of graphene can be performed by covalent and noncovalent modification techniques. In both cases, surface modification of graphene oxide followed by reduction has been carried out to obtain functionalized graphene.

What’s the difference between graphene and graphene oxide?

The key difference between graphene and graphene oxide is that graphene is a substance made of carbon atoms bonded to each other in a repeating pattern of hexagons, whereas graphene oxide is an oxidized form of graphene that is laced with groups having oxygen atoms.