Where do you inject hyaluronidase?

An intradermal injection of 4 to 8 units of hyaluronidase in the forearm and observing the results after 30 minutes has been advocated. However, it is recommended that a higher test dose of 20 units of hyaluronidase is used, as a positive reaction at lower doses might not be recognised.

What does the hyaluronidase enzyme do?

An enzyme that breaks down a substance in the body called hyaluronic acid. Hyaluronic acid is found throughout the body in connective tissue, skin, and fluids in the joints and inside the eye. It causes fluids to have a jelly-like thickness, which can help moisten and protect tissues and joints.

What is the half life of hyaluronidase?

Hyaluronidase has a half life of two minutes, but a duration of action of 24-48 hours due to its high potency.

What are the side effects of dissolving filler?

The obvious, immediate and most common side effect is slight bleeding after the needle has been inserted into the skin. Other risks include bruising, tenderness, redness and swelling around the injection site.

How is hyaluronidase administered?

With the patient prone, 75 Units of Hydase™ (hyaluronidase injection) is injected subcutaneously over each scapula, followed by injection of the contrast medium at the same sites.

How is hyaluronidase injected?

How is hyaluronidase given? Hyaluronidase is injected under the skin, into a muscle, or into other tissues of the body. A healthcare provider will give you this injection. Hyaluronidase should not be injected into a vein (as an intravenous injection).

Does filler ever fully dissolve?

While the filler itself doesn’t stay in your system, its effects last a lifetime. Hyaluronic acid, on the other hand, is non-permanent. Composed of a sugar molecule which is also produced naturally in the body, it generally dissolves and is excreted by the body in six to nine months.

Can hyaluronidase cause nerve damage?

“I had Hyaluronidase injections used on my face to dissolve filler and it has caused nerve damage, pain and burning sensation, dry eyes, blurred vision, it damaged my skin permanently.

What happens if you inject hyaluronidase?

Injection-related side effects including temporary swelling and bruising are the most common side effects from Hyaluronidase treatment. Allergy, including anaphylaxis, is an uncommon side effect of Hyaluronidase injections. It is more common in those who are allergic to bee-stings!

How long does hyaluronidase stay in your system?

Kim et al. [5] demonstrated that the effects of hyaluronidase dissipate within 3-6 hours post injection and that reinjection with hyaluronic acid fillers can be undertaken after 6 hours of using hyaluronidase.

Can hyaluronidase break up scar tissue?

Injection of hyaluronidase into the fibrotic scar lesion was effective in improving the pliability, height, and pigmentation of the fibrotic lesions by breaking down the ground substance of the connective tissue [1]. The VSS is used primarily as an index of scar after external wound.

Does hyaluronidase dissolve your own HA?

Though Hyaluronidase can dissolve your body’s own natural hyaluronic acid, hyaluronidase is not able to dissolve tissue. Hyaluronidase, either naturally occurring within the body or as an injection, is able to break down hyaluronic acid and only hyaluronic acid, which means that it cannot break down normal tissues.