Where is reticulin found?

Reticulin fibers support the body and are common in the liver, spleen and kidneys.

What is increased reticulin?

Increased reticulin staining (reticulin fibrosis) is associated with many benign and malignant conditions while increased trichrome staining (collagen fibrosis) is particularly prominent in late stages of severe myeloproliferative diseases or following tumour metastasis to the bone marrow.

What is the principle of reticulin staining?

Reticulin Stain Kit is a metal impregnation technique where ammoniacal silver initially binds to the tissue component of interest. Then the reducing agent (formalin) produces a dark insoluble precipitate, enabling silver to be reduced into a visible state.

What is bone marrow reticulin?

Reticulin is a normal component of the bone marrow stroma and can be detected with a reticulin stain in 73% to 81% of healthy subjects. 16-19. Increased reticulin staining (reticulin fibrosis) is associated with many benign conditions as well as some malignant diseases.

What is collagen fibers?

Collagen fibers are the structural elements found in vertebrate tissues that transmit forces, store, and dissipate energy. Collagen fibers limit the deformation of tendon and other load bearing tissues and have a hierarchical structure that includes collagen molecules, microfibrils, fibrils, fibers, and fascicles.

What is Leukoerythroblastosis?

Leukoerythroblastosis, as defined by Wintrobe, is the presence of immature cells of the myeloid series and nucleated red cells in the circulating blood, with or without anemia and is not seen exclusively in malignancies [7].

What is Trilineage hematopoiesis?

Trilineage hematopoiesis is a marker for how well your blood cell production system is working. If it’s reduced or increased, or if an abnormal number of other cells are present in your bone marrow, there may be a problem with your blood cell production system.

Where can I buy elastic fibers?

Elastic fibers are found in the skin, lungs, arteries, veins, connective tissue proper, elastic cartilage, periodontal ligament, fetal tissue and other tissues which must undergo mechanical stretching.

What is hairy cell leukemia?

Hairy cell leukemia is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). Leukemia may affect red blood cells, white blood cells, and platelets. Gender and age may affect the risk of hairy cell leukemia.

What is the principle of H and E?

The principle behind H & E stain is the chemical attraction between tissue and dye. Hematoxylin, a basic dye imparts blue-purple contrast on basophilic structures, primarily those containing nucleic acid moeties such as chromtatin, ribosomes and cytoplasmic regions rich in RNA.

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