Why tetracycline is contraindicated in pregnancy?

Certain other antibiotics are believed to pose risks during pregnancy. For example, tetracyclines can affect bone development and discolor a developing baby’s teeth. Tetracyclines aren’t recommended for use after the fifth week of pregnancy.

What are the contraindications of tetracycline?

Contraindications / Precautions

• Sulfite hypersensitivity, tartrazine dye hypersensitivity, tetracyclines hypersensitivity.
• Pregnancy.
• Children, infants, neonates.
• Breast-feeding.
• Renal disease, renal failure, renal impairment.
• Hepatic disease.
• Sunlight (UV) exposure.
• Surgery.

Does tetracycline cross the placenta?

Tetracycline crosses the human placenta and may cause a yellow-gray-brown tooth discoloration in adults after fetal/childhood exposure.

Why should tetracycline drugs be avoided during pregnancy and lactation?

Summary of Use during Lactation A number of reviews have stated that tetracycline is contraindicated during breastfeeding because of possible staining of infants’ dental enamel or bone deposition of tetracyclines.

Can tetracycline cause abortion?

Macrolides, quinolones, tetracyclines, sulfonamides and metronidazole were associated with an increased risk of “spontaneous abortion,” meaning loss of pregnancy before the 20th week of gestation.

Which antibiotic can not be taken by a pregnant woman or children under 8 years of age due to discoloration of the child’s teeth?

Older tetracycline-class antibiotics have been linked to cosmetic staining of permanent teeth when used in children before the age of 8 years. As a result, in 1970 a warning label was attached to all tetracycline-class antibiotics advising against the use in children under the age of 8 years.

Can antibiotics during pregnancy cause autism?

Background. Prenatal antibiotic exposure induces changes in infants’ gut microbiota composition and is suggested as a possible contributor in the development of autism spectrum disorders (ASD).

How many tetracycline do I take for abortion?

PIP: An evaluative study of the prophylactic use of tetracycline in 1st-trimester abortions is presented. 2 groups of 1000 patients received 1.5 gm of tetracycline hydrochloride, orally, 2-3 hours before the abortion procedure, followed by 500 mg every 6 hours for 4 days. 2 groups of 1000 patients served as controls.

Can tetracycline cause birth defects?

A small number of studies have investigated possible links between taking tetracycline, doxycycline, and oxytetracycline in the first trimester and specific birth defects. Overall, the current evidence does not raise alarm that birth defects are caused by use of these tetracyclines in pregnancy.

Does tetracycline affect early pregnancy?

“Tetracycline, for instance, at no time in pregnancy is safe because what it affects is the enamel, the lining of the bone and the teeth. So at any time in pregnancy that you use it, this can still cause an enamel malformation in that baby.

What kind of birth defects Do antibiotics Cause?

Children of mothers prescribed macrolide antibiotics during early pregnancy are at an increased risk of major birth defects, particularly heart defects, compared with children of mothers prescribed penicillin, finds a study published by The BMJ today.

Can tetracycline abort a pregnancy?

Antibiotics and Risk for Spontaneous Abortion In a study of 182,000 pregnant women, the use of certain antibiotics during early pregnancy was linked with a higher rate of miscarriage before 20 weeks. These antibiotics included quinolones, tetracyclines, sulfonamides, metronidazole, and macrolides (except erythromycin).