How many growth factors are in PRP?

The prominent growth factors of PRP, presented in Table 2, include platelet-derived growth factor (PDGF), transforming growth factor β (TGF-β), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), insulin-like growth factor (IGF) and fibroblast growth factor (FGF) [11, 12].

How do growth factors affect cell differentiation?

The effects of the growth factors on the overall representation of the different cells may result from their direct differentiation or from cell selection either by promoting proliferation or by inducing apoptosis of specific cell types.

What is the difference between growth factors and stem cells?

This means that rather than simply providing temporary pain relief, stem cells actually restore degenerated tissue and significantly reduce pain. Growth factors, on the other hand, are actually produced by stem cells themselves, as well as from platelets in the blood stream.

Are you born with a certain amount of stem cells?

Everybody is born with a certain amount of stem cells, specifically, “adult stem cells.” This number may be thought of as a type of “bank account”, from which each person may make “withdrawals” throughout his or her lifetime, as needed. However, not all bank accounts are created equal.

What is growth factor in PRP?

PRP is an autologous whole blood fraction that has a heavy amount of a variety of growth factors such as epidermal growth factor (EGF), Vascular Endothelial Growth Factor (VEGF), hepatocyte growth factor (HGF), fibroblast growth factors (FGFs), transforming growth factor beta-1 (TGF-b), insulin-like growth factor-I ( …

What are growth factors added in PRP?

What cells release growth factors?

They can be secreted by neighboring cells, distant tissues and glands, or even tumor cells themselves. Normal cells show a requirement for several growth factors to maintain proliferation and viability.